Pharmaceutical Excipients
Excipients for tablet, capsule, powder and liquid dosage forms. Larissa pharmacists advise on excipient selection for your formulation.
Seven excipient classes by role in the formulation
Excipients are selected by the job they do in the formulation, not by name. Below are the seven functional classes and what to weigh when choosing within each.
- 01
Fillers & diluents
Provide bulk and volume when the active is present at low dose, while shaping flow and compressibility.
When choosing: Check incompatibility with the active, and avoid lactose for lactose-intolerant target markets.
Typical examples in this class
- Microcrystalline cellulose
- Lactose monohydrate
- Dicalcium phosphate
- Mannitol
- Pregelatinised starch
- 02
Binders
Bind powder particles into robust granules so tablets survive compression and packaging.
When choosing: Excess binder hardens the tablet and prolongs disintegration.
Typical examples in this class
- Povidone (PVP)
- Copovidone
- HPMC
- Hydroxypropyl cellulose
- Starch paste
- 03
Disintegrants
Break the tablet apart in the gastrointestinal tract, governing how fast the active is released.
When choosing: Efficiency depends on whether it is added intragranularly, extragranularly or split between both.
Typical examples in this class
- Croscarmellose sodium
- Sodium starch glycolate
- Crospovidone
- Low-substituted HPC
- 04
Lubricants
Reduce friction between tablet and die wall, prevent punch sticking and ease ejection.
When choosing: Hydrophobic by nature — over-blending slows disintegration and lowers dissolution.
Typical examples in this class
- Magnesium stearate
- Stearic acid
- Sodium stearyl fumarate
- Talc
- 05
Glidants
Improve powder flow so the hopper feeds evenly and tablet weight stays uniform.
When choosing: Used at very low levels; beyond the optimum the effect reverses.
Typical examples in this class
- Colloidal silicon dioxide
- Talc
- 06
Film coating systems
Mask taste, protect from moisture, identify the product, or control where the active is released.
When choosing: Enteric coatings must resist gastric pH yet dissolve promptly in the small intestine.
Typical examples in this class
- HPMC-based systems
- PVA-based systems
- Methacrylic acid copolymers
- Ethylcellulose
- 07
Liquid dosage excipients
Stabilise syrups, suspensions and emulsions, with preservation and pH adjustment.
When choosing: The preservative system must be challenge-tested on the actual formulation, not inferred from another.
Typical examples in this class
- Xanthan gum
- Sodium carboxymethyl cellulose
- Polysorbate 80
- Sodium benzoate
- Citric acid / sodium citrate
The names above are typical examples within each functional class, not a stock list. Availability changes over time — send us the excipient and grade you need and we will confirm sourcing.
Which classes each form needs
Tablets
Filler · Binder · Disintegrant · Lubricant · Glidant · Coating
Hard capsules
Filler · Lubricant · Glidant
Powders & granules
Filler · Binder · Glidant · Sweetener and flavour
Liquids
Suspending · Emulsifying · Preservative · pH adjustment
Pellets
Operating since 2000, Spansules is among the most established pellet manufacturers in India, with GMP-standard facilities. The list below covers the products Larissa distributes.
| Ingredient | Therapeutic class | Form |
|---|---|---|
| Omeprazole EC | Proton pump inhibitor | Enteric coated |
| Esomeprazole EC | Proton pump inhibitor | Enteric coated |
| Lansoprazole EC | Proton pump inhibitor | Enteric coated |
| Pantoprazole | Proton pump inhibitor | — |
| Rabeprazole Sodium EC | Proton pump inhibitor | Enteric coated |
| Diclofenac Sodium SR | Non-steroidal anti-inflammatory | Sustained release |
| Domperidone IR/SR | Prokinetic | Immediate / sustained release |
| Itopride HCl SR | Prokinetic | Sustained release |
| Cinitapride SR | Prokinetic | Sustained release |
Working alongside your R&D team
Choosing an excipient is rarely about one material. It is a balance between compressibility, disintegration, stability and cost — and a change in one class pulls on the others.
Larissa pharmacists work with your R&D team on excipient selection and formulation troubleshooting, rather than simply fulfilling an order.
Need a quotation or a sample?
Send the ingredient name, grade and expected quantity. Our commercial team responds within one business day.